Portraying breast cancers with long noncoding RNAs

  title={Portraying breast cancers with long noncoding RNAs},
  author={Olivier Van Grembergen and M. Bizet and Eric De Bony and E. Calonne and Pascale Putmans and Sylvain Broh{\'e}e and C. Olsen and Mingzhou Guo and Gianluca Bontempi and C. Sotiriou and Matthieu Defrance and F. Fuks},
  journal={Science Advances},
  • Olivier Van Grembergen, M. Bizet, +9 authors F. Fuks
  • Published 2016
  • Biology, Medicine
  • Science Advances
  • Comprehensive analysis of the lncRNA landscape in breast cancers and its relationship with key clinical features and functional pathways. Evidence is emerging that long noncoding RNAs (lncRNAs) may play a role in cancer development, but this role is not yet clear. We performed a genome-wide transcriptional survey to explore the lncRNA landscape across 995 breast tissue samples. We identified 215 lncRNAs whose genes are aberrantly expressed in breast tumors, as compared to normal samples… CONTINUE READING
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