Portal hypertension correlates with splenic stiffness as measured with MR elastography.

@article{Nedredal2011PortalHC,
  title={Portal hypertension correlates with splenic stiffness as measured with MR elastography.},
  author={Geir I Nedredal and Meng Yin and Travis J Mckenzie and Joseph B. Lillegard and Jennifer Luebke-Wheeler and Jayant Talwalkar and Richard E Ehman and Scott L. Nyberg},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2011},
  volume={34 1},
  pages={79-87}
}
PURPOSE To investigate the correlation between MR elastography (MRE) assessed spleen stiffness and direct portal vein pressure gradient (D-HVPG) measurements in a large animal model of portal hypertension. MATERIALS AND METHODS Cholestatic liver disease was established in adult canines by common bile duct ligation. A spin echo based echo planar imaging (EPI) MRE sequence was used to acquire three-dimensional/three axis (3D/3-axis) abdominal MRE data at baseline, 4 weeks, and 8 weeks. Liver… CONTINUE READING