Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells.

@article{Boutrus2007PortableTI,
  title={Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells.},
  author={Steven Boutrus and Cherry Greiner and Derrick Hwu and Michael Kam-tim Chan and Charlotte Kuperwasser and Charles P. Lin and Irene Georgakoudi},
  journal={Journal of biomedical optics},
  year={2007},
  volume={12 2},
  pages={020507}
}
The recent introduction of the in vivo flow cytometer for real-time, noninvasive detection and quantification of cells circulating in the vasculature of small animals has provided a powerful tool for tracking the roles of different types of cells in disease progression. We describe a portable version of the device, which provides the capability to: a) excite and detect fluorescence at two distinct colors simultaneously, and b) perform data analysis in real time. These advances improve… CONTINUE READING

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