Port-site metastases. Impact of local tissue trauma and gas leakage.

  title={Port-site metastases. Impact of local tissue trauma and gas leakage.},
  author={Larissa N. L. Tseng and Frits J. Berends and Philippe Wittich and Nicole D Bouvy and Richard L. Marquet and Geert Kazemier and Hendrik J Bonjer},
  journal={Surgical endoscopy},
  volume={12 12},
BACKGROUND Port-site metastases after laparoscopic procedures in patients with digestive malignancies have evoked concern. The pathogenesis of port-site metastases remains unclear. Two experiments in rats were performed to determine the impact of both tissue trauma and leakage of CO2 along trocars (chimney effect) in the development of port-site metastases. METHODS Experiment I: Ten WAG rats had four 5-mm incisions in all abdominal quadrants. The incisions on the right side were crushed to… CONTINUE READING


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