Porphyromonas gingivalis fimbria-dependent activation of inflammatory genes in human aortic endothelial cells.

@article{Chou2005PorphyromonasGF,
  title={Porphyromonas gingivalis fimbria-dependent activation of inflammatory genes in human aortic endothelial cells.},
  author={Hsin-Hua Chou and Hiromichi Yumoto and Michael Davey and Yusuke Takahashi and Takanari Miyamoto and Frank C. Gibson and Caroline Attardo Genco},
  journal={Infection and immunity},
  year={2005},
  volume={73 9},
  pages={
          5367-78
        }
}
Epidemiological and pathological studies have suggested that infection with the oral pathogen Porphyromonas gingivalis can potentiate atherosclerosis and human coronary heart disease. Furthermore, infection with invasive, but not noninvasive P. gingivalis has been demonstrated to accelerate atherosclerosis in apolipoprotein E-deficient (ApoE(-/-)) mice and to accelerate local inflammatory responses in aortic tissue. In the present study, using high-density oligonucleotide microarrays, we have… CONTINUE READING
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Endothelial Chlamydia pneumoniae infection promotes oxidation of LDL.

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