Porphyromonas gingivalis downregulates the immune response of fibroblasts

  title={Porphyromonas gingivalis downregulates the immune response of fibroblasts},
  author={Eleonor Palm and Hazem Khalaf and Torbj{\"o}rn Bengtsson},
  booktitle={BMC Microbiology},
Porphyromonas gingivalis is a key pathogen in periodontitis, an inflammatory disease leading to destruction of bone and tooth-supporting tissue. P. gingivalis possesses a number of pathogenic properties to enhance growth and survival, including proteolytic gingipains. Accumulating data shows that gingipains are involved in the regulation of host inflammatory responses. The aim of this study was to determine if P. gingivalis infection modulates the inflammatory response of fibroblasts, including… CONTINUE READING
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