Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.

@article{Mikuls2012PorphyromonasGA,
  title={Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.},
  author={Ted R Mikuls and Geoffrey M Thiele and Kevin D. Deane and Jeffrey B Payne and James R. O'Dell and Fang Yu and Harlan S Sayles and Michael H. Weisman and Peter K. Gregersen and Jane H Buckner and Richard M Keating and Lezlie A. Derber and William H Robinson and V. Michael Holers and Jill M Norris},
  journal={Arthritis and rheumatism},
  year={2012},
  volume={64 11},
  pages={3522-30}
}
OBJECTIVE To examine the relationship of Porphyromonas gingivalis to the presence of autoantibodies in individuals at risk of rheumatoid arthritis (RA). METHODS Study participants included the following: 1) a cohort enriched in subjects with HLA-DR4 and 2) subjects at risk of RA by virtue of having a first-degree relative with RA. None of the study subjects satisfied the American College of Rheumatology 1987 classification criteria for RA. Autoantibodies measured included anti-citrullinated… CONTINUE READING
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