Porphyromonas gingivalis-Induced GEF Dock 180 Activation by Src / PKC δ-Dependent Phosphorylation Mediates PLC γ 2 Amplification in Salivary Gland Acinar Cells : Modulatory Effect of Ghrelin

@inproceedings{Slomiany2015PorphyromonasGG,
  title={Porphyromonas gingivalis-Induced GEF Dock 180 Activation by Src / PKC δ-Dependent Phosphorylation Mediates PLC γ 2 Amplification in Salivary Gland Acinar Cells : Modulatory Effect of Ghrelin},
  author={Bronislaw L. Slomiany and Amalia Slomiany},
  year={2015}
}
Phospholipase Cγ2 (PLCγ2) plays a pivotal role in mediation of inflammatory reaction to bacterial lipopolysaccharide (LPS) as well as serves as a key target in modulatory influence of the hormone ghrelin. Here we explore the involvement of Rac1 and its activator, guanine nucleotide exchange factor (GEF), Dock180, in mediation of PLCγ2 activation in salivary… CONTINUE READING