Porphyrin precursors and porphyrins in three patients with acute intermittent porphyria and end-stage renal disease under different therapy regimes.

@article{Sardh2009PorphyrinPA,
  title={Porphyrin precursors and porphyrins in three patients with acute intermittent porphyria and end-stage renal disease under different therapy regimes.},
  author={Eliane Sardh and Dan E. H. Andersson and Ann Henrichson and Pauline Harper},
  journal={Cellular and molecular biology},
  year={2009},
  volume={55 1},
  pages={66-71}
}
Porphyrin precursors and porphyrins were measured in three patients with recurrent attacks of acute intermittent porphyria and end-stage renal disease (ESRD): two patients on hemodialysis and one on peritoneal dialysis. Plasma porphobilinogen (PBG) and porphyrins were considerably increased in the three patients. In a previous study, the mean urinary and plasma PBG/ALA ratio in biochemically active AIP patients with conserved renal function was 2.0 (normal 0.3) and plasma porphyrin levels were… CONTINUE READING

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