Pore formation by a two-component leukocidin from Staphylococcus aureus within the membrane of human polymorphonuclear leukocytes.

@article{FinckBarbanon1993PoreFB,
  title={Pore formation by a two-component leukocidin from Staphylococcus aureus within the membrane of human polymorphonuclear leukocytes.},
  author={V Finck-Barbançon and Guy Duportail and Olivier Meunier and Didier A. Colin},
  journal={Biochimica et biophysica acta},
  year={1993},
  volume={1182 3},
  pages={
          275-82
        }
}
The effects of the Staphylococcus aureus leukocidin (PVL), a two-component non-hemolytic toxin, were investigated on the membrane permeability of human polymorphonuclear leukocytes (PMNs). In the absence of extracellular Ca2+, the fluorescence of ethidium bromide added to the extracellular medium increased after PVL application in a concentration-dependent manner and no variations in the free intracellular [Ca2+] of Fura2-loaded PMNs were detected. In the presence of extracellular Ca2+, the… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 37 CITATIONS

Similar Papers

Loading similar papers…