Porcine sperm motility is regulated by serine phosphorylation of the glycogen synthase kinase-3alpha.

@article{Aparicio2007PorcineSM,
  title={Porcine sperm motility is regulated by serine phosphorylation of the glycogen synthase kinase-3alpha.},
  author={In{\'e}s M. Aparicio and M J Bragado and Maria Cruz Gil and Manuel Garc{\'i}a-Herreros and L Gonz{\'a}lez-Fern{\'a}ndez and Jos{\'e} Antonio Rivera Tapia and L J Garcia-Marin},
  journal={Reproduction},
  year={2007},
  volume={134 3},
  pages={435-44}
}
Sperm functions are critically controlled through the phosphorylation state of specific proteins. Glycogen synthase kinase-3 (GSK3) is a serine/threonine kinase with two different isoforms (alpha and beta), the enzyme activity of which is inhibited by serine phosphorylation. Recent studies suggest that GSK3 is involved in the control of bovine sperm motility. Our aim was to investigate whether GSK3 is present in porcine spermatozoa and its role in the function of these cells. This work shows… CONTINUE READING