Porcine small diameter arterial extracellular matrix supports endothelium formation and media remodeling forming a promising vascular engineered biograft.

@article{Dahan2012PorcineSD,
  title={Porcine small diameter arterial extracellular matrix supports endothelium formation and media remodeling forming a promising vascular engineered biograft.},
  author={Nitsan Dahan and Gabriel Zarbiv and Udi Sarig and Tony Karram and Aaron Hoffman and Marcelle Machluf},
  journal={Tissue engineering. Part A},
  year={2012},
  volume={18 3-4},
  pages={411-22}
}
Patients with small caliber artery disorders, often lack the suitable autologous tissue needed for bypassing diseased vessels or for other vascular reconstructive procedures. We propose to decellularize small caliber porcine carotid artery, then recellularize it with vascular cells and function as scaffold for tissue engineering vascular graft replacements. Based on a modified decellularization method developed in our laboratory, the cellular contents of small caliber (<4 mm) arteries were… CONTINUE READING

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Decellularized tissue-engineered blood vessel as an arterial conduit.

Proceedings of the National Academy of Sciences of the United States of America • 2011
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