Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells.

Abstract

Porcine sialoadhesin (pSn; a sialic acid-binding lectin) and porcine CD163 (pCD163) are molecules that facilitate infectious entry of porcine reproductive and respiratory syndrome virus (PRRSV) into alveolar macrophages. In this study, it was shown that murine Sn (mSn) and human Sn (hSn), like pSn, can promote PRRSV infection of pCD163-expressing cells… (More)
DOI: 10.1099/vir.0.053082-0

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Cite this paper

@article{Breedam2013PorcineMA, title={Porcine, murine and human sialoadhesin (Sn/Siglec-1/CD169): portals for porcine reproductive and respiratory syndrome virus entry into target cells.}, author={Wander Van Breedam and Mieke Verbeeck and Isaura Christiaens and Hanne Van Gorp and Hans Nauwynck}, journal={The Journal of general virology}, year={2013}, volume={94 Pt 9}, pages={1955-60} }