Porcine encephalomyocarditis virus persists in pig myocardium and infects human myocardial cells.

@article{Brewer2001PorcineEV,
  title={Porcine encephalomyocarditis virus persists in pig myocardium and infects human myocardial cells.},
  author={Laurie Brewer and Humphrey C M Lwamba and Michael Murtaugh and Ann C. Palmenberg and Corrie J Brown and M Kariuki Njenga},
  journal={Journal of virology},
  year={2001},
  volume={75 23},
  pages={11621-9}
}
Recent advances toward using pig tissues in human transplantation have made it necessary to determine the risk of transmitting zoonotic viruses from pigs to humans or vice versa. We investigated the suitability of the porcine encephalomyocarditis virus (EMCV) model for such studies by determining its ability to persist in pigs, escape detection by routine serological methods, and infect human cells. Intraperitoneal inoculation of 5-week-old pigs with EMCV-30, a strain isolated from commercial… CONTINUE READING
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