Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor

@inproceedings{Kim2016PorcineSU,
  title={Porcine Sapelovirus Uses α2,3-Linked Sialic Acid on GD1a Ganglioside as a Receptor},
  author={Deok-Song Kim and Kyu-Yeol Son and Kyung-Min Koo and Ji-Yun Kim and Mia Madel Alfajaro and Jun-Gyu Park and Myra D T Hosmillo and Mahmoud Soliman and Yeong-Bin Baek and Eun-Hyo Cho and Ju-Hwan Lee and Mun-Il Kang and Ian Goodfellow and Kyoung-Oh Cho},
  booktitle={Journal of virology},
  year={2016}
}
UNLABELLED The receptor(s) for porcine sapelovirus (PSV), which causes diarrhea, pneumonia, polioencephalomyelitis, and reproductive disorders in pigs, remains largely unknown. Given the precedent for other picornaviruses which use terminal sialic acids (SAs) as receptors, we examined the role of SAs in PSV binding and infection. Using a variety of approaches, including treating cells with a carbohydrate-destroying chemical (NaIO4), mono- or oligosaccharides (N-acetylneuraminic acid, galactose… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 5 times over the past 90 days. VIEW TWEETS
7 Citations
46 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…