PorA Variable Regions of Neisseria meningitidis

  title={PorA Variable Regions of Neisseria meningitidis},
  author={Joanne E. Russell and Keith A. Jolley and Ian M. Feavers and Martin C J Maiden and Janet Suker},
  booktitle={Emerging infectious diseases},
Subtypes, defined by variation in the outer membrane protein PorA, are an integral part of the characterization scheme for Neisseria meningitidis. Identification of these variants remains important as the PorA protein is a major immunogenic component of several meningococcal vaccines under development, and characteristics of PorA are used to provide detailed epidemiologic information. Historically, serosubtypes have been defined by reactivity with a set of monoclonal antibodies. However… CONTINUE READING


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