Population study of allelic diversity in the human MHC class I-related MIC-A gene

Abstract

 The polymorphism of major histocompatibility complex (MHC) class I HLA-A, -B, and -C molecules may have evolved through pathogen-driven selection of alleles with diverse peptide-binding specificities. Two MHC-encoded molecules that are distantly related to class I, MIC-A and MIC-B, do not function in the presentation of pathogen-derived peptides to T cells… (More)
DOI: 10.1007/s002510050655

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