Population pharmacokinetics of vancomycin in neonates.

@article{Seay1994PopulationPO,
  title={Population pharmacokinetics of vancomycin in neonates.},
  author={R E Seay and Richard C Brundage and PD. Dr. M. Jensen and Craig G Schilling and B E Edgren},
  journal={Clinical pharmacology and therapeutics},
  year={1994},
  volume={56 2},
  pages={169-75}
}
OBJECTIVE To determine population pharmacokinetic parameters of vancomycin in neonates. METHODS This was a retrospective design, with prospective validation. Two hundred ten sequential neonates were evaluated at the neonatal intensive care units of Minneapolis Children's Medical Center and Children's Hospital of St. Paul. Five hundred twenty serum concentrations from 192 patients were included. A mean +/- SD gestational age of 29.5 +/- 5.1 weeks, postnatal age of 16.5 +/- 19.6 days, and… CONTINUE READING

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