Population pharmacokinetics of vancomycin in patients receiving extracorporeal membrane oxygenation.

@article{Mulla2005PopulationPO,
  title={Population pharmacokinetics of vancomycin in patients receiving extracorporeal membrane oxygenation.},
  author={Hussain Mulla and Suneel Kumar Pooboni},
  journal={British journal of clinical pharmacology},
  year={2005},
  volume={60 3},
  pages={265-75}
}
AIMS Extracorporeal membrane oxygenation (ECMO) is a life support system used during severe respiratory or cardiorespiratory failure. The objective of this study was to characterize the population pharmacokinetics of vancomycin during ECMO. METHODS A population model was developed using WinNonMix (Version 2.0.1) from a total of 366 plasma observations in 45 patients, including term neonates, older children and adults. The study utilized both rich prospective and sparse retrospective data… CONTINUE READING
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