Population pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery

@article{Sam2009PopulationPO,
  title={Population pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery},
  author={Wai Johnn Sam and Gregory Benson Hammer and David R. Drover},
  journal={BMC Anesthesiology},
  year={2009},
  volume={9},
  pages={5 - 5}
}
BACKGROUND The aim of this study was to provide a model-based analysis of the pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery with cardiopulmonary bypass (CPB). METHODS We studied nine patients aged 0.5 to 4 years who received a continuous remifentanil infusion via a computer-controlled infusion pump during cardiac surgery with mildly hypothermic CPB were studied. Arterial blood samples taken prior to, during and after CPB were analyzed for remifentanil… CONTINUE READING

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1 Excerpt

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