Population pharmacokinetics of faropenem in healthy human volunteers and patients

  title={Population pharmacokinetics of faropenem in healthy human volunteers and patients},
  author={Hideki Hirooka and Masahiro Sou and Koji Miyata and Kohya Shiba and Yusuke Tanigawara},
  journal={Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics},
Faropenem (FRPM) is an oral penem antibacterial medicine with a high stability to beta-lactamase which has a broad antibacterial spectrum and a strong antibacterial activity to gram positive bacteria, and gram negative bacteria, except for Pseudomonas aeruginosa and anaerobic bacteria. The sale of faropene was started in 1997.Based on the plasma faropenem concentration vs. time data obtained from clinical trials using healthy adult volunteers and patients, and a post-marketing clinical study… 
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