Population pharmacokinetic analysis of dalbavancin, a novel lipoglycopeptide.

  title={Population pharmacokinetic analysis of dalbavancin, a novel lipoglycopeptide.},
  author={Mary Buckwalter and James A. Dowell},
  journal={Journal of clinical pharmacology},
  volume={45 11},
Dalbavancin is a lipoglycopeptide antibiotic in clinical development as a once-weekly treatment for serious infections. A total of 532 patients, consisting of 502 patients with skin and soft tissue infections requiring parenteral therapy and 30 patients with catheter-related bloodstream infections, was available for population pharmacokinetic analysis. The majority of patients (78.4%) received dalbavancin intravenously as a 1000-mg dose on day 1 and a single 500-mg dose on day 8. A 2… CONTINUE READING

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