Population pharmacokinetic analysis during the first 2 years of life: an overview.

@article{Marsot2012PopulationPA,
  title={Population pharmacokinetic analysis during the first 2 years of life: an overview.},
  author={Am{\'e}lie Marsot and Audrey Boulam{\'e}ry and Bernard Bruguerolle and Nicolas Simon},
  journal={Clinical pharmacokinetics},
  year={2012},
  volume={51 12},
  pages={
          787-98
        }
}
Three decades after its introduction, pharmacokinetic population approaches have become a reference method for drug modelling, particularly in paediatrics. The main practical limitation in this specific population is the collected blood volume. Pharmacokinetic population approaches using sparse sampling may resolve this issue. The pharmacokinetics of many drugs have been studied during the last 25 years using such methods. This review summarizes all of the published studies concerning… CONTINUE READING
Highly Cited
This paper has 21 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Pharmacokinetic Variability in Pediatrics and Intensive Care: Toward a Personalized Dosing Approach.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 113 references

Meropenem pharmacokinetics in the newborn.

Antimicrobial agents and chemotherapy • 2009
View 9 Excerpts
Highly Influenced

Population pharmacokinetics of cefepime in the neonate.

Antimicrobial agents and chemotherapy • 2005
View 7 Excerpts
Highly Influenced

Population pharmacokinetics of rectal theophylline in neonates.

Therapeutic drug monitoring • 1991
View 11 Excerpts
Highly Influenced

Population pharmacokinetics of gentamicin in neonates.

Developmental pharmacology and therapeutics • 1988
View 4 Excerpts
Highly Influenced

Neonatal population pharmacokinetics of phenobarbital derived from routine clinical data.

Developmental pharmacology and therapeutics • 1985
View 4 Excerpts
Highly Influenced