Population imaging of ongoing neuronal activity in the visual cortex of awake rats

  title={Population imaging of ongoing neuronal activity in the visual cortex of awake rats},
  author={David S. Greenberg and Arthur R. Houweling and Jason N. D. Kerr},
  journal={Nature Neuroscience},
It is unclear how the complex spatiotemporal organization of ongoing cortical neuronal activity recorded in anesthetized animals relates to the awake animal. We therefore used two-photon population calcium imaging in awake and subsequently anesthetized rats to follow action potential firing in populations of neurons across brain states, and examined how single neurons contributed to population activity. Firing rates and spike bursting in awake rats were higher, and pair-wise correlations were… CONTINUE READING
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AN 0 C or re la tio n 0 10 20 Action potentials across population

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Error bars represent s.e.m. NATURE NEUROSCIENCE VOLUME • 2001

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