Population genomics of the wild yeast Saccharomyces paradoxus: Quantifying the life cycle.

@article{Tsai2008PopulationGO,
  title={Population genomics of the wild yeast Saccharomyces paradoxus: Quantifying the life cycle.},
  author={Isheng J Tsai and Douda Bensasson and Austin Burt and Vassiliki Koufopanou},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 12},
  pages={4957-62}
}
Most microbes have complex life cycles with multiple modes of reproduction that differ in their effects on DNA sequence variation. Population genomic analyses can therefore be used to estimate the relative frequencies of these different modes in nature. The life cycle of the wild yeast Saccharomyces paradoxus is complex, including clonal reproduction, outcrossing, and two different modes of inbreeding. To quantify these different aspects we analyzed DNA sequence variation in the third… CONTINUE READING
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