Population genomics of Chlamydia trachomatis: insights on drift, selection, recombination, and population structure.

@article{Joseph2012PopulationGO,
  title={Population genomics of Chlamydia trachomatis: insights on drift, selection, recombination, and population structure.},
  author={Sandeep J. Joseph and Xavier Didelot and James Rothschild and Henry John Christiaan de Vries and Servaas A Morr{\'e} and Timothy D. Read and Deborah Dean},
  journal={Molecular biology and evolution},
  year={2012},
  volume={29 12},
  pages={3933-46}
}
The large number of sexually transmitted diseases and ocular trachoma cases that are caused globally each year by Chlamydia trachomatis has made this organism a World Health Organization priority for vaccine development. However, there is no gene transfer system for Chlamydia to help identify potential vaccine targets. To accelerate discoveries toward this goal, here we analyzed the broadest diversity of C. trachomatis genomes to date, including 25 geographically dispersed clinical and seven… CONTINUE READING
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