Population genomics in bacteria: a case study of Staphylococcus aureus.

@article{Takuno2012PopulationGI,
  title={Population genomics in bacteria: a case study of Staphylococcus aureus.},
  author={Shohei Takuno and Tomoyuki Kado and Ryuichi P. Sugino and Luay Nakhleh and Hideki Innan},
  journal={Molecular biology and evolution},
  year={2012},
  volume={29 2},
  pages={797-809}
}
We analyzed the genome-wide pattern of single nucleotide polymorphisms (SNPs) in a sample with 12 strains of Staphylococcus aureus. Population structure of S. aureus seems to be complex, and the 12 strains were divided into five groups, named A, B, C, D, and E. We conducted a detailed analysis of the topologies of gene genealogies across the genomes and observed a high rate and frequency of tree-shape switching, indicating extensive homologous recombination. Most of the detected recombination… CONTINUE READING
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