Population genetic structure of Plasmodium falciparum in the two main African vectors, Anopheles gambiae and Anopheles funestus.

@article{Annan2007PopulationGS,
  title={Population genetic structure of Plasmodium falciparum in the two main African vectors, Anopheles gambiae and Anopheles funestus.},
  author={Zeinab Annan and Patrick Durand and Francisco J. Ayala and C{\'e}line Arnathau and Parfait H. Awono-Amb{\'e}n{\'e} and Fr{\'e}d{\'e}ric Simard and Fabien G. Razakandrainibe and Jacob C. Koella and Didier Fontenille and François N.R. Renaud},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2007},
  volume={104 19},
  pages={7987-92}
}
We investigated patterns of genetic diversity of Plasmodium falciparum associated with its two main African vectors: Anopheles gambiae and Anopheles funestus. We dissected 10,296 wild-caught mosquitoes from three tropical sites, two in Cameroon (Simbock and Tibati, separated by 320 km) and one in Kenya (Rota, >2,000 km from the other two sites). We assayed seven microsatellite loci in 746 oocysts from 183 infected mosquito guts. Genetic polymorphism was very high in parasites isolated from both… CONTINUE READING