Population genetic nature of copy number variation.

  title={Population genetic nature of copy number variation.},
  author={Per Sj{\"o}din and Mattias Jakobsson},
  journal={Methods in molecular biology},
Copy number variation has recently received considerable attention, and copy number variants (CNVs) have been shown to be both common in mammalian genomes and important for understanding genetic and phenotypic variation. As empirical knowledge and detection methods are quickly advancing, evolutionary theories about CNVs are rapidly updated and often revised. Here, we review recent progress on understanding CNVs, and we discuss some key issues for future research. In essence, we discuss four… CONTINUE READING

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