Population dynamics and in vitro antibody pressure of porcine parvovirus indicate a decrease in variability.

@article{Streck2013PopulationDA,
  title={Population dynamics and in vitro antibody pressure of porcine parvovirus indicate a decrease in variability.},
  author={Andr{\'e} Felipe Streck and Timo Homeier and Tessa Foerster and Uwe Truyen},
  journal={The Journal of general virology},
  year={2013},
  volume={94 Pt 9},
  pages={
          2050-5
        }
}
To estimate the impact of porcine parvovirus (PPV) vaccines on the emergence of new phenotypes, the population dynamic history of the virus was calculated using the Bayesian Markov chain Monte Carlo method with a Bayesian skyline coalescent model. Additionally, an in vitro model was performed with consecutive passages of the 'Challenge' strain (a virulent field strain) and NADL2 strain (a vaccine strain) in a PK-15 cell line supplemented with polyclonal antibodies raised against the vaccine… CONTINUE READING

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Porcine parvovirus. In Diseases of Swine, 10th edn, pp. 447–455

  • U. Truyen, A. F. Streck
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