Population-based study of the risk of second primary contralateral breast cancer associated with carrying a mutation in BRCA1 or BRCA2.

@article{Malone2010PopulationbasedSO,
  title={Population-based study of the risk of second primary contralateral breast cancer associated with carrying a mutation in BRCA1 or BRCA2.},
  author={Kathleen E. Malone and Colin B. Begg and Robert W Haile and Ake Borg and Patrick Concannon and Lina Tellhed and Shanyan Xue and Sharon N. Teraoka and Leslie Bernstein and Marinela Capanu and Anne S. Reiner and Elyn R. Riedel and Duncan C Thomas and Lene Mellemkjaer and Charles F. Lynch and John Dunning Boice and Hoda Anton-Culver and Jonine L. Bernstein},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2010},
  volume={28 14},
  pages={
          2404-10
        }
}
PURPOSE Women with breast cancer diagnosed early in life comprise a substantial portion of those tested for BRCA1/BRCA2 mutations; however, little information is available on the subsequent risks of contralateral breast cancer in mutation carriers. This study assessed the risk of subsequent contralateral breast cancer associated with carrying a BRCA1 or BRCA2 mutation. PATIENTS AND METHODS In this nested case-control study, patients with contralateral breast cancer diagnosed 1 year or more… CONTINUE READING
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