Population-based study of pseudoprogression after chemoradiotherapy in GBM.

  title={Population-based study of pseudoprogression after chemoradiotherapy in GBM.},
  author={Gloria B. Rold{\'a}n and J Nicholson Scott and John B. McIntyre and M. W. N. Dharmawardene and Paula A de Robles and Anthony M. Magliocco and Elizabeth S Y Yan and Ian F. Parney and Peter A. Forsyth and J. Gregory Cairncross and Mark G. Hamilton and Jacob C. Easaw},
  journal={The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques},
  volume={36 5},
INTRODUCTION Chemoradiotherapy followed by monthly temozolomide (TMZ) is the standard of care for patients with glioblastoma multiforme (GBM). Case reports have identified GBM patients who experienced transient radiological deterioration after concurrent chemoradiotherapy which stabilized or resolved after additional cycles of adjuvant TMZ, a phenomenon known as radiographic pseudoprogression. Little is known about the natural history of radiographic pseudoprogression. METHODS We… CONTINUE READING
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