Population-based study of glutathione S-transferase mu gene deletion in adult glioma cases and controls.

@article{Wiencke1997PopulationbasedSO,
  title={Population-based study of glutathione S-transferase mu gene deletion in adult glioma cases and controls.},
  author={John K. Wiencke and Margaret R. Wrensch and Rei Miike and Z. F. Zuo and Karl T. Kelsey},
  journal={Carcinogenesis},
  year={1997},
  volume={18 7},
  pages={1431-3}
}
Gene deletion at the glutathione S-transferase mu locus (GSTM1) has previously been associated with increased risk for environmentally-induced cancers (e.g. smoking-related lung cancer). In the present study we examined the hypothesis that GSTM1 deletion is a risk factor for malignant brain tumors in adults. We compared the prevalence of the GSTM1 homozygous deletion polymorphism in 158 Caucasian adults with gliomas with 157 controls. Cases and controls were drawn from a large population-based… CONTINUE READING
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