Population-based studies of myocardial hypertrophy: high resolution cardiovascular magnetic resonance atlases improve statistical power

@inproceedings{Marvao2014PopulationbasedSO,
  title={Population-based studies of myocardial hypertrophy: high resolution cardiovascular magnetic resonance atlases improve statistical power},
  author={Antonio de Marvao and Timothy J W Dawes and Wenzhe Shi and Christopher Minas and Niall Keenan and Tamara Diamond and Giuliana Durighel and Giovanni Montana and Daniel Rueckert and Stuart A. Cook and Declan P. O’Regan},
  booktitle={Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance},
  year={2014}
}
BACKGROUND Cardiac phenotypes, such as left ventricular (LV) mass, demonstrate high heritability although most genes associated with these complex traits remain unidentified. Genome-wide association studies (GWAS) have relied on conventional 2D cardiovascular magnetic resonance (CMR) as the gold-standard for phenotyping. However this technique is insensitive to the regional variations in wall thickness which are often associated with left ventricular hypertrophy and require large cohorts to… CONTINUE READING
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