Population-based genetic and evolutionary analysis of Chlamydia trachomatis urogenital strain variation in the United States.

@article{Millman2004PopulationbasedGA,
  title={Population-based genetic and evolutionary analysis of Chlamydia trachomatis urogenital strain variation in the United States.},
  author={Kim Millman and C. Black and Robert E. Johnson and Walter E. Stamm and Robert B. Jones and Edward W. Hook and David H. Martin and Gail A. Bolan and Simon Tavar{\'e} and Deborah Dean},
  journal={Journal of bacteriology},
  year={2004},
  volume={186 8},
  pages={2457-65}
}
Chlamydia trachomatis is a major cause of ocular and sexually transmitted diseases worldwide. While much of our knowledge about its genetic diversity comes from serotyping or ompA genotyping, no quantitative assessment of genetic diversity within serotypes has been performed. To accomplish this, 507 urogenital samples from a multicenter U.S. study were analyzed by phylogenetic and statistical modeling. No B, Da, or I serotypes were represented. Based on our analyses, all but one previous… CONTINUE READING

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