Population-based case control study of the safety of sulfasalazine use during pregnancy.


BACKGROUND We studied the human teratogenic risk of sulfasalazine because this drug interferes with folate metabolism. METHODS Case control study within the Hungarian Case Control Surveillance of Congenital Abnormalities, 1980-1996; based on 22 865 new-born infants or foetuses with congenital abnormalities, and 38 151 babies without any detected… (More)


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