Population-based case control study of the safety of sulfasalazine use during pregnancy.

@article{Nrgrd2001PopulationbasedCC,
  title={Population-based case control study of the safety of sulfasalazine use during pregnancy.},
  author={Bente Mertz N{\o}rg{\aa}rd and Andrew E. Czeizel and Magda Rockenbauer and J{\o}rn Olsen and Henrik Toft S{\o}rensen},
  journal={Alimentary pharmacology & therapeutics},
  year={2001},
  volume={15 4},
  pages={
          483-6
        }
}
BACKGROUND We studied the human teratogenic risk of sulfasalazine because this drug interferes with folate metabolism. METHODS Case control study within the Hungarian Case Control Surveillance of Congenital Abnormalities, 1980-1996; based on 22 865 new-born infants or foetuses with congenital abnormalities, and 38 151 babies without any detected congenital abnormalities (control group). RESULTS Seventeen pregnant women (0.07%) were treated with sulfasalazine in the case group, and 26 (0.07… CONTINUE READING

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