Population Structure in the Mediterranean Basin: A Y Chromosome Perspective

@article{Capelli2006PopulationSI,
  title={Population Structure in the Mediterranean Basin: A Y Chromosome Perspective},
  author={Cristian Capelli and Nicola J. Redhead and Val{\'e}ria Romano and Francesco Cal{\`i} and G{\'e}rard Lefranc and Val{\'e}rie Delague and Andr{\'e} M{\'e}garban{\'e} and Alex Felice and Vincenzo L Pascali and Pavlos I Neophytou and Z Poulli and Andrea Novelletto and Patrizia Malaspina and Luciano Terrenato and A Berebbi and M. Fellous and Mark George Thomas and David B. Goldstein},
  journal={Annals of Human Genetics},
  year={2006},
  volume={70}
}
The Mediterranean region has been characterised by a number of pre-historical and historical demographic events whose legacy on the current genetic landscape is still a matter of debate. [] Key Method In order to investigate the degree of population structure across the Mediterranean, we have investigated Y chromosome variation in a large dataset of Mediterranean populations, 11 of which are first described here. Our analyses identify four main clusters in the Mediterranean that can be labelled as North…
Geographical Structure of the Y‐chromosomal Genetic Landscape of the Levant: A coastal‐inland contrast
TLDR
A coastal‐inland, east‐west pattern of diversity and frequency distribution in several haplogroups within the small region of the Levant is found, likely to have arisen mainly from differential migrations, with different lineages introduced from the east and west.
Y chromosome variation in Europe: Continental and local processes in the formation of the extant gene pool
TLDR
The emerging picture for the composition of the male gene pool of the continent is illustrated, but local peculiarities that represent departures from the main trends are also highlighted, in order to illustrate the main unifying feature, i.e. the overlay of recent patterns onto more ancient ones.
Introducing the Algerian Mitochondrial DNA and Y-Chromosome Profiles into the North African Landscape
TLDR
A sample of 240 unrelated subjects from a northwest Algeria cosmopolitan population was analyzed using mtDNA sequences and Y-chromosome biallelic polymorphisms, focusing on the fine dissection of haplogroups E and R, which are the most prevalent in North Africa and Europe respectively.
Mediterranean Y-chromosome 2.0—why the Y in the Mediterranean is still relevant in the postgenomic era
TLDR
The aim was to demonstrate that the Y-chromosome still provides important insights in the postgenomic era and in a time when ancient genomes are becoming exponentially available.
The Mediterranean Human Population: An Anthropological Genetics Perspective
TLDR
This comprehensive approach allows to trace genetic profiles of Mediterranean populations into the past to discover and reconstruct their origins and demographic histories, as well as their evolutionary relationships.
Turkish Cypriot paternal lineages bear an autochthonous character and closest resemblance to those from neighbouring Near Eastern populations
TLDR
Turkish Cypriot paternal lineages seem to bear an autochthonous character and closest genetic connection with the neighbouring Near Eastern populations, further underscored by the fact that the haplogroups associated with the spread of Neolithic Agricultural Revolution from the Fertile Crescent dominate the Turkish Cypriots' haplogroup distribution.
Moors and Saracens in Europe: estimating the medieval North African male legacy in southern Europe
TLDR
The results point to a higher recent Northwest African contribution in Iberia and Sicily in agreement with historical data, and southern Italian regions known to have experienced long-term Arab presence show an enrichment of Northwest African types.
Human genetic differentiation across the Strait of Gibraltar
TLDR
It is shown that gene flow across the Strait of Gibraltar occurred at relatively high rates since pre-Neolithic times and that natural selection and sex-bias migrations distorted the demographic signal at some specific loci of the authors' genome.
Archaeogenetics and Landscape Dynamics in Sicily during the Holocene: A Review
The Mediterranean islands and their population history are of considerable importance to the interpretation of the population history of Europe as a whole. In this context, Sicily, because of its
...
...

References

SHOWING 1-10 OF 68 REFERENCES
Genetic structure of Mediterranean populations revealed by Y-chromosome haplotype analysis.
TLDR
The spatial distribution of DYS392 alleles revealed a marked differentiation between the East and the West of the Mediterranean area, suggesting that at least part of the male-specific gene pools of these populations has either a very recent common origin (that could be related with the Neolithic demic diffusion hypothesis), and/or that gene flow has played a significant role in shaping the patterns of genetic variability in this region.
Reduced genetic structure of the Iberian peninsula revealed by Y-chromosome analysis: implications for population demography
TLDR
The results indicate that neither old or recent Levantine expansions nor North African contacts have influenced the current Iberian Y-chromosome diversity so that geographical patterns can be identified.
Joining the Pillars of Hercules: mtDNA Sequences Show Multidirectional Gene Flow in the Western Mediterranean
TLDR
The AMOVA demonstrates that SW European populations are highly homogeneous whereas NW African populations display a more heterogeneous genetic pattern, due to an east‐west differentiation as a result of gene flow coming from the East.
A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa.
TLDR
The Neolithic transition in this part of the world was accompanied by demic diffusion of Afro-Asiatic-speaking pastoralists from the Middle East, and it is suggested that the North African pattern of Y-chromosomal variation is largely of Neolithic origin.
A multistep process for the dispersal of a Y chromosomal lineage in the Mediterranean area.
TLDR
A microsatellite-defined Y-chromosomal lineage identified by us and reported in previous studies, whose geographic distribution and antiquity appear to be compatible with the Neolithic spread of farmers suggests that its spread was associated to a population expansion, with a high rate of male gene flow in the Turkish-Greek area.
Africans and Asians abroad: genetic diversity in Europe.
TLDR
How knowledge of the patterns of genetic diversity in Europe, and of their inferred generating processes, can be extremely useful in planning health care and in biomedical research is discussed.
Y‐chromosome Lineages from Portugal, Madeira and Açores Record Elements of Sephardim and Berber Ancestry
TLDR
The present composition of the Y chromosomes in Portugal in this haplogroup likely reflects a pre‐Arab component shared with North African populations or testifies, at least in part, to the influence of Sephardic Jews.
The genetic legacy of Paleolithic Homo sapiens sapiens in extant Europeans: a Y chromosome perspective.
TLDR
A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.
Geographic patterns of mtDNA diversity in Europe.
TLDR
The distribution of the zones of highest mitochondrial variation (genetic boundaries) confirmed that the Saami are sharply differentiated from an otherwise rather homogeneous set of European samples, and an area of significant clinal variation was identified around the Mediterranean Sea (and not in the north), even though the differences between northern and southern populations were insignificant.
A signal, from human mtDNA, of postglacial recolonization in Europe.
TLDR
The present study shows that the dissection of mtDNA variation into small and well-defined evolutionary units is an essential step in the identification of spatial frequency patterns, and promises to be an efficient strategy for inferring features of human prehistory.
...
...