Population Structure in Contemporary Sweden—A Y‐Chromosomal and Mitochondrial DNA Analysis

@article{Lappalainen2009PopulationSI,
  title={Population Structure in Contemporary Sweden—A Y‐Chromosomal and Mitochondrial DNA Analysis},
  author={Tuuli Lappalainen and Ulf Hannelius and Elina Salmela and Ulrika von D{\"o}beln and Cecilia M. Lindgren and Kirsi Huoponen and M-L. Savontaus and Juha Kere and P{\"a}ivi Lahermo},
  journal={Annals of Human Genetics},
  year={2009},
  volume={73}
}
A population sample representing the current Swedish population was analysed for maternally and paternally inherited markers with the aim of characterizing genetic variation and population structure. The sample set of 820 females and 883 males were extracted and amplified from Guthrie cards of all the children born in Sweden during one week in 2003. 14 Y‐chromosomal and 34 mitochondrial DNA SNPs were genotyped. The haplogroup frequencies of the counties closest to Finland, Norway, Denmark and… Expand
Mitochondrial DNA analysis of Swedish population samples
As a contribution to the geographic coverage of EMPOP, currently the best available forensic mitochondrial DNA (mtDNA) database, a total of 299 Swedish individuals were analysed by sequencing of theExpand
Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe
TLDR
The data suggest a small eastern contribution among the Finns, consistent with the historical and linguistic background of the population, and illustrate that population history is often important for patterns of genetic variation, and that the analysis of hundreds of thousands of SNPs provides high resolution also for population genetics. Expand
Finnish population genetics in a forensic context
TLDR
The results of this study suggest that while these markers were well suited for individualization purposes, they were inefficient for paternity testing in the Finnish population, highlighting the need for careful population-specific validation of commercial marker sets widely in use in forensics. Expand
Swedish Population Substructure Revealed by Genome-Wide Single Nucleotide Polymorphism Data
TLDR
The internal structure within Sweden was stronger than that in many Central European populations, although smaller than what has been observed for instance in Finland; importantly, it is of the magnitude that may hamper association studies with a moderate number of markers if cases and controls are not properly matched geographically. Expand
The place of Slovakian paternal diversity in the clinal European landscape
TLDR
It was found that the male diversity of Slovakia is embedded in the clinal pattern of the major R1a and R1b clades extending over the continent and a similar pattern of population structure is found with Y-specific SNP or STR variation. Expand
Y‐Chromosomal Lineages of Latvians in the Context of the Genetic Variation of the Eastern‐Baltic Region
TLDR
More than a third of Latvian paternal lineages belong specifically to a recently defined R1a‐M558 hg, indicating an influence from a common source within Eastern Slavic populations on the formation of the present‐dayLatvian Y‐chromosome gene pool. Expand
The history and geography of the Y chromosome SNPs in Europe: an update.
TLDR
The state of the art of the phylogenetic and phylogeographic research on Y chromosome SNP analyses in Europe is reported, updating the review published in this Journal by Francalacci & Sanna at the beginning of 2008. Expand
Vestiges of an Ancient Border in the Contemporary Genetic Diversity of North-Eastern Europe
TLDR
The results coupled with prior archeological evidence suggest the genetic northeast/southwest division observed in contemporary Finland represents an ancient vestigial border between Mesolithic and Neolithic populations undetectable in most other regions of Europe. Expand
Peopling of the North Circumpolar Region – Insights from Y Chromosome STR and SNP Typing of Greenlanders
TLDR
The results indicate that Inuit individuals carrying the Q-NWT01 (xM265) lineage may have their origin in the northeastern parts of North America and could be descendants of the Dorset culture, which points to the possibility that the current Inuit population in Greenland is comprised of individuals of both Thule and Dorset descent. Expand
Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool
TLDR
The phylogeographic analyses reveal that two mitochondrial DNA lineages, N3 and N1a3, might mark distinct events of matrilineal gene flow to Europe: during the mid-Holocene period and around the Pleistocene- Holocene transition, respectively. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 41 REFERENCES
Y-chromosome diversity in Sweden – A long-time perspective
TLDR
Y chromosomes within haplogroup R1b3 were found to have the highest STR variation among all haplogroups and could thus be considered to be one of the earliest major male lineages present in Sweden. Expand
Migration Waves to the Baltic Sea Region
TLDR
It was shown that the populations surrounding the Baltic Sea are genetically similar, which suggests that it has been an important route not only for cultural transmission but also for population migration. Expand
Population substructure in Finland and Sweden revealed by the use of spatial coordinates and a small number of unlinked autosomal SNPs
TLDR
The power to cluster individuals based on their genetic similarity is increased when including information about the spatial coordinates, and the importance of estimating the size and effect of genotyping error in population genetics is demonstrated in order to strengthen the validity of the results. Expand
Y-chromosome STR haplotypes in Sweden.
TLDR
The haplotype 14, 12, 28, 23, 10, 11, 13, 14-14 has the highest frequency and is significantly Swedish, when compared to other European populations. Expand
The western and eastern roots of the Saami--the story of genetic "outliers" told by mitochondrial DNA and Y chromosomes.
TLDR
A high-resolution phylogenetic analysis of Saami genetic heritage was undertaken in a comprehensive context, through use of maternally inherited mitochondrial DNA (mtDNA) and paternALLY inherited Y-chromosomal variation, and it was shown that the "Saami motif" variant of mtDNA haplogroup U5b is present in a large area outside Scandinavia. Expand
The phylogeography of Y chromosome binary haplotypes and the origins of modern human populations
TLDR
A set of unique event polymorphisms associated with the non‐recombining portion of the Y‐chromosome (NRY) addresses this issue by providing evidence concerning successful migrations originating from Africa, which can be interpreted as subsequent colonizations, differentiations and migrations overlaid upon previous population ranges. Expand
Tracing European founder lineages in the Near Eastern mtDNA pool.
TLDR
There has been substantial back-migration into the Near East, there was a founder effect or bottleneck associated with the Last Glacial Maximum, 20,000 years ago, and a way to account for multiple dispersals of common sequence types is suggested. Expand
Phylogenetic network for European mtDNA.
TLDR
The nucleotide sequence in the coding region of mtDNA was determined from 121 Finns, by conformation-sensitive gel electrophoresis and subsequent sequencing and by direct sequencing of the D loop, which allowed the compilation of unambiguous phylogenetic networks. Expand
Regional differences among the Finns: a Y-chromosomal perspective.
TLDR
The results gave further support to the existence of a sharp genetic border between eastern and western Finns so far observed exclusively in Y-chromosomal variation and suggested that the western and eastern parts of the country have been subject to partly different population histories. Expand
Mitochondrial DNA variation of modern Tuscans supports the near eastern origin of Etruscans.
TLDR
Interpopulation comparisons reveal that the modern population of Murlo, a small town of Etruscan origin, is characterized by an unusually high frequency (17.5%) of Near Eastern mtDNA haplogroups, supporting a direct and rather recent genetic input from the Near East--a scenario in agreement with the Lydian origin of ETruscans. Expand
...
1
2
3
4
5
...