Population Pharmacokinetics of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

@article{Isla2008PopulationPO,
  title={Population Pharmacokinetics of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy},
  author={Arantxazu Isla and Alicia Rodr{\'i}guez-Gasc{\'o}n and I{\~n}aki F. Troc{\'o}niz and Lorea Bueno and Mar{\'i}a {\'A}ngeles Solin{\'i}s and J Melis Maynar and Jos{\'e} Angel S{\'a}nchez-Izquierdo and Jos{\'e} Luis Pedraz},
  journal={Clinical Pharmacokinetics},
  year={2008},
  volume={47},
  pages={173-180}
}
AbstractBackground and objective: Meropenem is a carbapenem antibacterial frequently prescribed for the treatment of severe infections in critically ill patients, including those receiving continuous renal replacement therapy (CRRT). The objective of this study was to develop a population pharmacokinetic model of meropenem in critically ill patients undergoing CRRT. Patients and methods: A prospective, open-label study was conducted in 20 patients undergoing CRRT. Blood and dialysate… CONTINUE READING
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