Population Pharmacokinetics of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy

@article{Isla2008PopulationPO,
  title={Population Pharmacokinetics of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy},
  author={A. Isla and A. Rodr{\'i}guez-Gasc{\'o}n and I. Troc{\'o}niz and L. Bueno and M. A. Solin{\'i}s and J. Maynar and J. S{\'a}nchez-Izquierdo and J. Pedraz},
  journal={Clinical Pharmacokinetics},
  year={2008},
  volume={47},
  pages={173-180}
}
  • A. Isla, A. Rodríguez-Gascón, +5 authors J. Pedraz
  • Published 2008
  • Medicine
  • Clinical Pharmacokinetics
  • AbstractBackground and objective: Meropenem is a carbapenem antibacterial frequently prescribed for the treatment of severe infections in critically ill patients, including those receiving continuous renal replacement therapy (CRRT). The objective of this study was to develop a population pharmacokinetic model of meropenem in critically ill patients undergoing CRRT. Patients and methods: A prospective, open-label study was conducted in 20 patients undergoing CRRT. Blood and dialysate… CONTINUE READING
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