Population Pharmacokinetics and Pharmacodynamics of Doripenem in Obese, Hospitalized Patients.


BACKGROUND Doripenem population pharmacokinetics and dosing recommendations are limited in obesity. OBJECTIVE To evaluate the population pharmacokinetics and pharmacodynamics of doripenem in obese patients. METHODS Hospitalized adults with a body mass index (BMI) ≥ 40 kg/m2 or total body weight (TBW) ≥45.5 kg over their ideal body weight received… (More)
DOI: 10.1177/1060028016676831


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