Population Pharmacokinetic Study of Amoxicillin-treated Burn Patients Hospitalized at a Tertiary Swiss Centre.

Objectives: To investigate the population pharmacokinetics (PK) of amoxicillin in ICU burn patients and the optimal dosage regimens. METHODS Prospective study involving 21 consecutive burn patients receiving amoxicillin. PK data were analysed using non-linear mixed effects modelling. Monte-Carlo simulations assessed the influence of various amoxicillin… CONTINUE READING