Population Pharmacokinetic Modeling of Subcutaneously Administered Etanercept in Patients with Psoriasis

Abstract

The objective of this paper is to present a population PK model which adequately describes the time–concentration profiles of different doses of etanercept (Enbrel®) administered subcutaneously to subjects with moderate-to-severe psoriasis and to simulate the time courses of concentrations following 50 mg once weekly (QW) dosing. Pharmacokinetic (PK) data… (More)
DOI: 10.1007/s10928-005-5912-0

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