Poor survival for infants with MYCN-amplified metastatic neuroblastoma despite intensified treatment: the International Society of Paediatric Oncology European Neuroblastoma Experience.

@article{Caete2009PoorSF,
  title={Poor survival for infants with MYCN-amplified metastatic neuroblastoma despite intensified treatment: the International Society of Paediatric Oncology European Neuroblastoma Experience.},
  author={Adela Ca{\~n}ete and Mary Gerrard and Herv{\'e} Rubi{\'e} and V Castel and Andrea di Cataldo and Caroline Munzer and Ruth Ladenstein and B{\'e}n{\'e}dicte Brichard and Jos{\'e} D. Berm{\'u}dez and J{\'e}r{\^o}me Couturier and Bruno de Bernardi and Andrew D. J. Pearson and Jean Marie Michon},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2009},
  volume={27 7},
  pages={1014-9}
}
PURPOSE To report the results of a prospective, nonrandomized European study on infants with neuroblastoma and MYCN gene amplification. PATIENTS AND METHODS Infants with neuroblastoma (stage 2, 3, 4, and 4s) and MYCN gene amplification who were diagnosed between 1999 and 2004 were eligible for enrollment onto the study. After diagnosis, staging, and mandatory biologic studies, induction chemotherapy (IC) with conventional drugs was administered, followed by delayed surgery, megatherapy… CONTINUE READING

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