Poor sleep is associated with higher plasma proinflammatory cytokine interleukin-6 and procoagulant marker fibrin D-dimer in older caregivers of people with Alzheimer's disease.

@article{Knel2006PoorSI,
  title={Poor sleep is associated with higher plasma proinflammatory cytokine interleukin-6 and procoagulant marker fibrin D-dimer in older caregivers of people with Alzheimer's disease.},
  author={Roland von K{\"a}nel and Joel E. Dimsdale and Sonia Ancoli-Israel and Paul J. Mills and Thomas L Patterson and Christine L McKibbin and Christopher Archuleta and Igor Grant},
  journal={Journal of the American Geriatrics Society},
  year={2006},
  volume={54 3},
  pages={431-7}
}
OBJECTIVES To determine whether objective measures of sleep correlate with plasma levels of the proinflammatory cytokine interleukin (IL)-6 and the procoagulant marker fibrin D-dimer in caregivers of patients with dementia. DESIGN Cross-sectional study. SETTING Subjects' homes. PARTICIPANTS Sixty-four community-dwelling spousal caregivers (69% women, mean age+/-standard deviation 72+/-9) and 36 sex-matched noncaregiving controls. MEASUREMENTS All participants underwent in-home full… CONTINUE READING

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