Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes.

@article{Ozanne1997PoorFN,
  title={Poor fetal nutrition causes long-term changes in expression of insulin signaling components in adipocytes.},
  author={Susan E Ozanne and Barbara T. Nav{\'e} and Chun Lin Wang and P. R. Shepherd and Johanna H. Prins and Geoffrey Douglas Smith},
  journal={The American journal of physiology},
  year={1997},
  volume={273 1 Pt 1},
  pages={
          E46-51
        }
}
Insulin action on adipocytes was studied in the offspring of mothers who had been fed either a control (20% protein) or a low (8%)-protein diet during pregnancy and lactation. Adipocytes isolated from low-protein offspring had significantly higher basal and insulin-stimulated glucose uptakes than controls. This may be related to a threefold increase in insulin receptors in low-protein adipocytes. Consistent with these observed changes in glucose transport, adipocytes from low-protein animals… CONTINUE READING
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