Poor adherence to placebo or amiodarone therapy predicts mortality: results from the CAMIAT study. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial.

@article{Irvine1999PoorAT,
  title={Poor adherence to placebo or amiodarone therapy predicts mortality: results from the CAMIAT study. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial.},
  author={Jane Irvine and Brian Baker and Juliana A Smith and S Jandciu and Miney Paquette and Joan Cairns and Stuart D. Connolly and R. S. Roberts and Michael J. Gent and P. Dorian},
  journal={Psychosomatic medicine},
  year={1999},
  volume={61 4},
  pages={566-75}
}
OBJECTIVE This study examined the relationship between adherence, mortality, and psychosocial factors. METHODS Subjects were 1141 patients participating in the Canadian Amiodarone Myocardial Infarction Arrhythmia Trial. Poor adherence to study medication (amiodarone or placebo), measured by pill count over 2 years, was defined as the lower 20th percentile of the pill count distribution. Predictors of adherence were also studied and included demographic and cardiac variables and, in a subset… CONTINUE READING

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