Poor adherence to oral bisphosphonate treatment and its consequences: a review of the evidence.

@article{Rabenda2009PoorAT,
  title={Poor adherence to oral bisphosphonate treatment and its consequences: a review of the evidence.},
  author={V{\'e}ronique Rabenda and Micha{\"e}l Hiligsmann and J -Y Reginster},
  journal={Expert opinion on pharmacotherapy},
  year={2009},
  volume={10 14},
  pages={2303-15}
}
Poor therapeutic adherence is a major issue faced by physicians today. This paper summarizes the adherence rates with oral bisphosphonate (OBP) treatment in clinical practice and their impact on clinical outcomes. Studies systematically demonstrated that overall compliance and persistence with OBPs among osteoporotic women are poor. Although extending dosing intervals improved adherence, the gains are suboptimal. Most importantly, low compliance and persistence rates consistently resulted in… CONTINUE READING

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