Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting

Abstract

Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overcome these constraints. Dried blood spots from finger pricks have been shown to be more practical than the use of plasma specimens, and pooling strategies using plasma specimens have been demonstrated to be an efficient method to reduce costs. This study found that combination of finger-prick dried blood spots and a pooling strategy is a feasible and efficient option to reduce costs, while maintaining accuracy in the context of a district hospital in Malawi.

DOI: 10.1097/QAI.0b013e3182a61e63

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Cite this paper

@inproceedings{Pannus2013PooledHV, title={Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting}, author={Pieter Pannus and Emmanuel Fajardo and Carol Ann Metcalf and Rebecca Marie Coulborn and Laura Trivi{\~n}o Duran and Helen Bygrave and Tom Ellman and Daniela Belen Garone and Michael Mitchell Murowa and Reuben Mwenda and Tony Reid and Wolfgang Preiser}, booktitle={Journal of acquired immune deficiency syndromes}, year={2013} }