Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat

@article{Shannon2004PontineRG,
  title={Pontine respiratory group neuron discharge is altered during fictive cough in the decerebrate cat},
  author={R. Shannon and David M. Baekey and K. F. Morris and S. C. Nuding and Lauren S. Segers and B. G. Lindsey},
  journal={Respiratory Physiology \& Neurobiology},
  year={2004},
  volume={142},
  pages={43-54}
}
A network of neurons in the rostral dorsal lateral pons and pons/mescencephalic junction constitute the pontine respiratory group (PRG) and is essential for reflex cough. As a next step in understanding the role of the PRG in the expression of the cough reflex, we examined neuron firing rates during fictive cough in cats. Decerebrated, thoracotomized, paralyzed, cycle-triggered ventilated adult cats were used. Extracellular activity of many single neurons and phrenic and lumbar neurograms were… 
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TLDR
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The Kölliker‐Fuse nucleus gates the postinspiratory phase of the respiratory cycle to control inspiratory off‐switch and upper airway resistance in rat
TLDR
It is concluded that descending KF inputs are essential to gate PI activity required for a proper pattern formation and phase control within the respiratory network, at least during absence of pulmonary stretch receptor activity and that the KF contains large numbers of laryngeal PI premotor neurons that might have a key role in the regulation of upper airway resistance during reflex control and vocalization.
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